Hi
The current evidence on choice of fluids for resuscitation in children with infections is weak, say the authors of this systematic review. Samuel Akech and colleagues say that while existing trials have provided important evidence in malaria and dengue, resuscitation in children with paediatric sepsis, for which colloids could be of benefit, has not been studied. The evidence from existing studies is not robust enough to make any definitive recommendations over the choice of resuscitation fluid and a definitive trial is required to address this. In a linked editorial Joseph Carcillo says that isotonic crystalloids are advised in early resuscitation, and colloids in late resuscitation.
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